SCHEMBL23398453

SCHEMBL23398453

Cc1ccc(-n2nc(CC(C)C)cc2O)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCKAR P32238 9/20 0.41
ALDH1A1 P00352 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
PTGS2 P35354 1/20 0.38
CA9 Q16790 1/20 0.38
POLB P06746 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
RXRA P19793 1/20 0.37
RXRB P28702 1/20 0.37
RXRG P48443 1/20 0.37
CACNA1G O43497 1/20 0.37
CACNA1H O95180 1/20 0.37
KCNH2 Q12809 1/20 0.37
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
TP53 P04637 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23400074 0.87 CACNA1H (0.47) ALDH1A1CACNA1GCACNA1HKCNH2TLR7
SCHEMBL23398871 0.85 CA1 (0.41) ALDH1A1CA1CA2MEN1NPC1
SCHEMBL23403350 0.85 ALDH1A1 (0.44) CCKARALDH1A1L3MBTL1NPC1TP53
SCHEMBL23399441 0.82 KDM5A (0.41) ALDH1A1CA1CA2PTGS2CA9
SCHEMBL23398638 0.79 ALDH1A1 (0.45) ALDH1A1CA1CA2PTGS2CA9
SCHEMBL23400782 0.79 ALDH1A1 (0.41) ALDH1A1L3MBTL1MAPTKMT2ATLR7
SCHEMBL23401415 0.77 CNR1 (0.49) ALDH1A1CA1CA2PTGS2CA9
SCHEMBL23399290 0.77 KCNJ6 (0.50) ALDH1A1PTGS2POLBTDP1L3MBTL1
SCHEMBL23401563 0.75 CACNA1G (0.40) ALDH1A1CACNA1GCACNA1HKCNH2MEN1
SCHEMBL11441588 0.74 CYP1A2 (0.47) ALDH1A1POLBMEN1NPC1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed