SCHEMBL23398476

SCHEMBL23398476

CCCn1[nH]cc(-c2ccc(C)cc2)c1=O

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
LMNA P02545 2/20 0.42
ADORA2A P29274 3/20 0.41
ADORA2B P29275 3/20 0.41
GAA P10253 3/20 0.39
KDM4E B2RXH2 2/20 0.39
HTT P42858 1/20 0.36
MEN1 O00255 2/20 0.35
NPC1 O15118 2/20 0.35
KMT2A Q03164 2/20 0.35
BRD4 O60885 1/20 0.35
TP53 P04637 1/20 0.35
HPGD P15428 1/20 0.34
ERCC1 P07992 1/20 0.34
ERCC5 P28715 1/20 0.34
FEN1 P39748 1/20 0.34
ERCC4 Q92889 1/20 0.34
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23403303 0.91 RGS4 (0.40) ALDH1A1LMNAADORA2AADORA2BGAA
SCHEMBL23400881 0.87 MEN1 (0.36) ALDH1A1LMNAADORA2AADORA2BGAA
SCHEMBL23398866 0.85 ALDH1A1 (0.47) ALDH1A1ADORA2AADORA2BGAAKDM4E
SCHEMBL23402689 0.82 ALDH1A1 (0.42) ALDH1A1GAAKDM4EMEN1KMT2A
SCHEMBL23403296 0.79 RGS4 (0.39) ALDH1A1GAAHTTMEN1NPC1
SCHEMBL23403534 0.78 MEN1 (0.39) LMNAADORA2AADORA2BGAAMEN1
SCHEMBL23402186 0.76 ALDH1A1 (0.45) ALDH1A1GAAKDM4ENPC1BRD4
SCHEMBL23398967 0.76 MEN1 (0.52) ALDH1A1ADORA2AADORA2BGAAKDM4E
SCHEMBL23401059 0.73 ALDH1A1 (0.61) ALDH1A1ADORA2AADORA2BGAAKDM4E
SCHEMBL23402975 0.71 MEN1 (0.59) ALDH1A1GAAKDM4EMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed