SCHEMBL23398483

SCHEMBL23398483

CCc1nn(-c2ccc(C)cc2)cc1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 11/20 0.56
RAB9A P51151 9/20 0.56
ALDH1A1 P00352 6/20 0.56
SMN1; SMN2 Q16637 4/20 0.56
KDM4E B2RXH2 5/20 0.43
LMNA P02545 3/20 0.43
MAPT P10636 4/20 0.43
NOTUM Q6P988 2/20 0.42
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
NFKB1 P19838 2/20 0.41
NFKB2 Q00653 2/20 0.41
RELA Q04206 2/20 0.41
CASP3 P42574 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
ADORA3 P0DMS8 1/20 0.40
GLA P06280 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23402990 0.87 NPC1 (0.54) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL7012292 0.84 RAB9A (0.54) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL23403020 0.84 NPC1 (0.51) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL23398521 0.82 NPC1 (0.49) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL23400147 0.82 RAB9A (0.52) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL23400078 0.81 ADORA3 (0.45) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL23402828 0.78 NPC1 (0.54) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL23402380 0.76 NPC1 (0.52) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL23402521 0.74 KMT2A (0.55) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL14019468 0.74 NOTUM (0.51) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed