SCHEMBL23398492

SCHEMBL23398492

CCCc1cnn(-c2ccccc2C)c1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 2/20 0.42
MAPK14 Q16539 1/20 0.41
SMO Q99835 1/20 0.38
ALDH1A1 P00352 6/20 0.38
LMNA P02545 2/20 0.38
MAPT P10636 2/20 0.38
KDM4E B2RXH2 1/20 0.38
TP53 P04637 1/20 0.38
MEN1 O00255 1/20 0.37
PKM P14618 1/20 0.37
KMT2A Q03164 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
NPBWR1 P48145 1/20 0.37
HSD11B1 P28845 1/20 0.36
GRM5 P41594 1/20 0.36
GRM1 Q13255 1/20 0.36
TSHR P16473 1/20 0.36
FLT3 P36888 1/20 0.35
GSK3B P49841 1/20 0.35
APLNR P35414 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23399778 0.91 HIF1A (0.41) HIF1AMAPK14SMOALDH1A1LMNA
SCHEMBL23398645 0.88 MAPK14 (0.46) HIF1AMAPK14SMOALDH1A1LMNA
SCHEMBL23398554 0.81 MEN1 (0.41) HIF1AMAPK14SMOALDH1A1LMNA
SCHEMBL23402338 0.80 USP2 (0.47) SMOALDH1A1LMNAMAPTPKM
SCHEMBL23398914 0.79 HIF1A (0.45) HIF1AMAPK14SMOALDH1A1LMNA
SCHEMBL23400221 0.79 MAPK14 (0.48) HIF1AMAPK14ALDH1A1LMNAMAPT
SCHEMBL23402994 0.75 RAB9A (0.43) HIF1ASMOALDH1A1LMNAMAPT
SCHEMBL23398388 0.75 MAPT (0.42) ALDH1A1LMNAMAPTKDM4ETP53
SCHEMBL23401279 0.73 MAPK14 (0.43) HIF1AMAPK14ALDH1A1LMNAMAPT
SCHEMBL23399939 0.72 ALDH1A1 (0.47) HIF1AMAPK14ALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed