SCHEMBL23398558

SCHEMBL23398558

CC(C)Cc1nn(-c2ccccc2)c(-c2ccccc2)c1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 4/20 0.44
CYP2C19 P33261 4/20 0.44
CYP1A2 P05177 2/20 0.44
CACNA1H O95180 2/20 0.40
ALDH1A1 P00352 7/20 0.40
CYP3A4 P08684 2/20 0.39
PTGS2 P35354 1/20 0.39
MAPT P10636 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
HTR2A P28223 1/20 0.37
HTR2C P28335 1/20 0.37
HTR2B P41595 1/20 0.37
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
MAPK1 P28482 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
GAA P10253 1/20 0.36
KDM4C Q9H3R0 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23398475 0.92 CYP2C9 (0.41) CYP2C9CYP2C19CYP1A2CACNA1HALDH1A1
SCHEMBL23399478 0.92 ALDH1A1 (0.41) CYP2C9CYP2C19CYP1A2CACNA1HALDH1A1
SCHEMBL23402262 0.88 RPA1 (0.44) ALDH1A1NPC1RAB9AL3MBTL1GAA
SCHEMBL23398600 0.88 ALDH1A1 (0.45) CYP2C9CYP2C19CYP1A2CACNA1HALDH1A1
SCHEMBL23402593 0.88 RPA1 (0.45) CYP2C9CYP2C19CYP1A2ALDH1A1MAPT
SCHEMBL23403096 0.85 HIF1A (0.42) CYP2C9CYP2C19CYP1A2CACNA1HALDH1A1
SCHEMBL23402598 0.84 PTGS2 (0.43) CYP2C9CYP2C19CYP1A2CYP3A4PTGS2
SCHEMBL23402858 0.83 ALDH1A1 (0.49) CYP2C9CYP2C19CYP1A2ALDH1A1CYP3A4
SCHEMBL23401952 0.82 CACNA1H (0.50) CYP2C9CYP2C19CYP1A2CACNA1HALDH1A1
SCHEMBL23402477 0.82 KDM4C (0.51) CYP2C9CYP2C19CYP1A2CACNA1HALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed