SCHEMBL23398677

SCHEMBL23398677

CCCn1nc(CC)cc1O

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.40
ADORA2B P29275 1/20 0.40
ESR1 P03372 3/20 0.37
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
HCAR3 P49019 1/20 0.32
POLB P06746 1/20 0.32
GRM2 Q14416 1/20 0.32
CYP1A2 P05177 1/20 0.32
SLC9A1 P19634 1/20 0.32
SMYD3 Q9H7B4 1/20 0.31
HPGD P15428 1/20 0.31
TYR P14679 1/20 0.31
NAMPT P43490 1/20 0.31
GLS O94925 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23402142 0.88 ESR1 (0.40) ESR1CNR1CNR2HCAR3POLB
SCHEMBL23399344 0.86 ADORA2A (0.39) ADORA2AADORA2BESR1CNR1CNR2
SCHEMBL19091622 0.83 ADORA2A (0.36) ADORA2AADORA2BESR1
SCHEMBL23401138 0.82 NPC1 (0.37) ADORA2AADORA2BESR1CNR1CNR2
SCHEMBL23402391 0.81 ADORA2A (0.36) ADORA2AADORA2BESR1POLBCYP1A2
SCHEMBL23398627 0.79 ADORA2B (0.44) ADORA2AADORA2BESR1POLBCYP1A2
SCHEMBL587459 0.78
SCHEMBL23403172 0.78 ADORA2A (0.39) ADORA2AADORA2BESR1CNR1CNR2
SCHEMBL11647899 0.77 ADORA2A (0.33) ADORA2AADORA2BESR1CNR1CNR2
SCHEMBL18198140 0.77 ADORA2A (0.41) ADORA2AADORA2BESR1CYP1A2SLC9A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed