⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23401592 | 0.83 | POLB (0.40) | — | |
| SCHEMBL589646 | 0.80 | — | — | |
| SCHEMBL31261225 | 0.80 | — | — | |
| SCHEMBL23403442 | 0.79 | NPC1 (0.37) | — | |
| SCHEMBL23398677 | 0.78 | ADORA2A (0.40) | — | |
| SCHEMBL19091622 | 0.77 | ADORA2A (0.36) | — | |
| SCHEMBL23136478 | 0.77 | PRKCE (0.33) | — | |
| SCHEMBL23400805 | 0.77 | GABRA1 (0.36) | — | |
| SCHEMBL18811454 | 0.76 | — | — | |
| SCHEMBL2844335 | 0.75 | KDM4E (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025202003-A1 | POLYMERISATION INHIBITORS | BASF SE (DE) | 2025-10-02 | — | — | WO | disclosed |
| US-20250195480-A1 | MACROCYCLIC AZOLOPYRIDINE DERIVATIVES AS EED AND PRC2 MODULATORS | Fulcrum Therapeutics, Inc. | 2025-06-19 | — | — | US | disclosed |
| US-12109198-B2 | Macrocyclic azolopyridine derivatives as EED and PRC2 modulators | Fulcrum Therapeutics, Inc. (US) | 2024-10-08 | — | — | US | disclosed |
| US-20240139163-A1 | MACROCYCLIC AZOLOPYRIDINE DERIVATIVES AS EED AND PRC2 MODULATORS | Fulcrum Therapeutics, Inc. | 2024-05-02 | — | — | US | disclosed |
| CN-114144230-B | Macrocyclic azolopyridine derivatives as EED and PRC2 modulators | 弗尔康医疗公司 | 2024-04-23 | — | — | CN | disclosed |
| WO-2023240138-A1 | INDAZOLE CONTAINING MACROCYCLES AND THEIR USE | BLOSSOMHILL THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| US-11661413-B2 | Pyrazole compounds or salts thereof, preparation method therefor, herbicidal composition and use thereof | QINGDAO KINGAGROOT CHEMICAL COMPOUNDS CO., LTD. (CN) | 2023-05-30 | — | — | US | disclosed |
| US-11661413-B2 | Pyrazole compounds or salts thereof, preparation method therefor, herbicidal composition and use thereof | QINGDAO KINGAGROOT CHEMICAL COMPOUNDS CO., LTD. (CN) | 2023-05-30 | — | — | US | disclosed |
| US-11661413-B2 | Pyrazole compounds or salts thereof, preparation method therefor, herbicidal composition and use thereof | QINGDAO KINGAGROOT CHEMICAL COMPOUNDS CO., LTD. (CN) | 2023-05-30 | — | — | US | disclosed |
| WO-2023066372-A1 | AZAINDOLE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF, AND HERBICIDE | 山东先达农化股份有限公司 | 2023-04-27 | — | — | WO | disclosed |
| EP-2081925-A1 | BENZOYLPYRAZOLES, THEIR USE AS AS HERBICIDES, AND INTERMEDIATES | Bayer CropScience AG (DE) | 2009-07-29 | — | — | EP | disclosed |
| WO-2009052138-A1 | PREPARATION OF DIHYDROTHIENO [3, 2-D] PYRIMIDINES AND INTERMEDIATES USED THEREIN | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-23 | — | — | WO | disclosed |
| WO-2008043456-A1 | BENZOYLPYRAZOLES, THEIR USE AS AS HERBICIDES, AND INTERMEDIATES | BAYER CROPSCIENCE AG (DE) | 2008-04-17 | — | — | WO | disclosed |
| EP-1781662-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | Pfizer, Inc. (US) | 2007-05-09 | — | — | EP | disclosed |
| US-20070015764-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | AGOURON PHARMACEUTICALS, INC. | 2007-01-18 | — | — | US | disclosed |
| US-20070015764-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | AGOURON PHARMACEUTICALS, INC. | 2007-01-18 | — | — | US | disclosed |
| US-20070015764-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | AGOURON PHARMACEUTICALS, INC. | 2007-01-18 | — | — | US | disclosed |
| US-7151105-B2 | Inhibitors of Hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same | AGOURON PHARMACEUTICALS, INC. (US) | 2006-12-19 | — | — | US | disclosed |
| US-20060122399-A1 | Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same | AGOURON PHARMACEUTICALS, INC. | 2006-06-08 | — | — | US | disclosed |
| WO-2006018725-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2006-02-23 | — | — | WO | disclosed |