SCHEMBL23398688

SCHEMBL23398688

CCCc1c(O)cnn1-c1cccc(C)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.48
RAB9A P51151 4/20 0.48
PAX8 Q06710 1/20 0.48
KMT2A Q03164 1/20 0.44
ALDH1A1 P00352 5/20 0.43
MAPT P10636 4/20 0.43
LMNA P02545 3/20 0.43
GAA P10253 2/20 0.43
MAPK1 P28482 2/20 0.43
KDM4E B2RXH2 3/20 0.42
HTT P42858 1/20 0.42
BLM P54132 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TP53 P04637 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
SMO Q99835 1/20 0.41
MAPK14 Q16539 2/20 0.40
HSD11B1 P28845 1/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23399765 0.92 LMNA (0.46) NPC1RAB9APAX8KMT2AALDH1A1
SCHEMBL23402637 0.88 NPC1 (0.47) NPC1RAB9APAX8KMT2AALDH1A1
SCHEMBL23399438 0.83 NR4A3 (0.53) RAB9AALDH1A1MAPTLMNAGAA
SCHEMBL23402167 0.82 ALDH1A1 (0.49) NPC1RAB9AALDH1A1MAPTLMNA
SCHEMBL23402757 0.82 NPC1 (0.45) NPC1RAB9APAX8KMT2AALDH1A1
SCHEMBL23401254 0.80 NPC1 (0.45) NPC1RAB9APAX8KMT2AALDH1A1
SCHEMBL23399056 0.79 NPC1 (0.51) NPC1RAB9APAX8KMT2AALDH1A1
SCHEMBL23401733 0.77 ALDH1A1 (0.43) NPC1RAB9APAX8ALDH1A1MAPT
SCHEMBL23400426 0.77 ALDH1A1 (0.47) ALDH1A1MAPTLMNAMAPK1TP53
SCHEMBL23402779 0.76 ALDH1A1 (0.42) NPC1RAB9APAX8ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed