SCHEMBL23398806

SCHEMBL23398806

Cc1ccccc1-c1nn(-c2ccccc2)c(O)c1-c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.44
MEN1 O00255 4/20 0.44
NPC1 O15118 4/20 0.44
RAB9A P51151 4/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
HIF1A Q16665 2/20 0.41
DCTPP1 Q9H773 1/20 0.40
MAPT P10636 4/20 0.40
ALDH1A1 P00352 2/20 0.40
MAPK1 P28482 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
PTGS2 P35354 3/20 0.39
PTGS1 P23219 2/20 0.39
KDM4A O75164 1/20 0.39
LMNA P02545 2/20 0.39
KDM4E B2RXH2 1/20 0.39
GAA P10253 1/20 0.39
HPGD P15428 1/20 0.39
STAT6 P42226 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23403114 0.93 DCTPP1 (0.41) KMT2AMEN1NPC1RAB9ASMN1; SMN2
SCHEMBL23399883 0.93 CCNA2 (0.44) KMT2AMEN1NPC1RAB9ASMN1; SMN2
SCHEMBL23403642 0.90 RPA1 (0.49) KMT2AMEN1NPC1RAB9ASMN1; SMN2
SCHEMBL23401161 0.89 MAPT (0.43) KMT2AMEN1NPC1RAB9ASMN1; SMN2
SCHEMBL23400678 0.88 CA1 (0.51) KMT2AMEN1SMN1; SMN2ALDH1A1LMNA
SCHEMBL23403209 0.87 ALDH1A1 (0.45) KMT2AMEN1NPC1RAB9ASMN1; SMN2
SCHEMBL23399775 0.84 KMT2A (0.50) KMT2AMEN1NPC1RAB9ASMN1; SMN2
SCHEMBL23400873 0.83 DCTPP1 (0.43) KMT2AMEN1SMN1; SMN2HIF1ADCTPP1
SCHEMBL23400859 0.82 CCNA2 (0.52) KMT2AMEN1NPC1RAB9ASMN1; SMN2
SCHEMBL23400965 0.82 CCNA2 (0.52) KMT2AMEN1NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed