SCHEMBL23398982

SCHEMBL23398982

CCc1c(-c2ccc(C)cc2)nn(-c2ccc(C)c(C)c2)c1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.41
CYP1A2 P05177 3/20 0.41
CYP2C19 P33261 3/20 0.41
TSHR P16473 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
LMNA P02545 2/20 0.41
TP53 P04637 2/20 0.41
CYP3A4 P08684 2/20 0.41
MAPT P10636 2/20 0.41
CYP2C9 P11712 2/20 0.41
ESR1 P03372 2/20 0.41
KDM4E B2RXH2 1/20 0.41
GMNN O75496 1/20 0.41
USP2 O75604 1/20 0.41
CYP2D6 P10635 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
NFKB1 P19838 1/20 0.41
MAPK1 P28482 1/20 0.41
THPO P40225 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23402097 0.90 KMT2A (0.51) KMT2ACYP1A2CYP2C19TSHRNPSR1
SCHEMBL23399712 0.90 CA1 (0.50) KMT2ACYP1A2CYP2C19TSHRNPSR1
SCHEMBL23403111 0.89 KMT2A (0.50) KMT2ACYP1A2CYP2C19TSHRNPSR1
SCHEMBL23401683 0.89 LMNA (0.44) KMT2ACYP1A2CYP2C19TSHRNPSR1
SCHEMBL23400959 0.86 CA1 (0.42) KMT2ANFKB1CA1CA2ALDH1A1
SCHEMBL23401069 0.86 KMT2A (0.36) KMT2ACYP1A2CYP2C19TSHRNPSR1
SCHEMBL23402053 0.84 ALDH1A1 (0.40) KMT2ACYP1A2CYP2C19TSHRNPSR1
SCHEMBL23400067 0.83 CA1 (0.41) KMT2ACYP1A2CYP2C19TSHRNPSR1
SCHEMBL23399026 0.83 CA1 (0.44) KMT2ACYP1A2CYP2C19TSHRNPSR1
SCHEMBL23400994 0.82 SMN1; SMN2 (0.44) KMT2ACYP1A2CYP2C19TSHRNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed