SCHEMBL23399006

SCHEMBL23399006

Cc1ccccc1-n1cc(C(C)(C)C)c(O)n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.41
GABRB2 P47870 1/20 0.41
ADORA3 P0DMS8 3/20 0.40
ADORA2A P29274 2/20 0.40
FLT3 P36888 1/20 0.38
GSK3B P49841 1/20 0.38
ALDH1A1 P00352 3/20 0.36
TSHR P16473 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ATP4A P20648 1/20 0.36
ATP4B P51164 1/20 0.36
MAPK13 O15264 1/20 0.36
MAPK12 P53778 1/20 0.36
MAPK11 Q15759 1/20 0.36
MAPK14 Q16539 1/20 0.36
RXRA P19793 5/20 0.35
GRIN1 Q05586 5/20 0.35
GRIN2B Q13224 5/20 0.35
CA2 P00918 1/20 0.33
GRM5 P41594 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23399059 0.83 ADORA3 (0.45) ADORA3ADORA2AFLT3GSK3BALDH1A1
SCHEMBL23399312 0.78 ESR2 (0.42) ALDH1A1TSHRTDP1HPGDSMN1; SMN2
SCHEMBL23402790 0.77 ADORA3 (0.40) GABRA1GABRB2ADORA3ADORA2AFLT3
SCHEMBL28947953 0.77 ADORA3 (0.41) ADORA3ADORA2AFLT3GSK3BALDH1A1
SCHEMBL23403679 0.77 ADORA3 (0.41) ADORA3ADORA2AFLT3GSK3BALDH1A1
SCHEMBL23401239 0.74 HSP90AA1 (0.42) GABRA1GABRB2ADORA3ADORA2AFLT3
SCHEMBL11825632 0.74 ADORA3 (0.43) ADORA3ADORA2AFLT3GSK3BALDH1A1
SCHEMBL23401684 0.74 ADORA3 (0.42) ADORA3ADORA2AFLT3GSK3BALDH1A1
SCHEMBL23399098 0.73 NPC1 (0.42) ADORA3ADORA2AALDH1A1CA2HPGD
SCHEMBL23398420 0.73 ADORA3 (0.39) ADORA3ADORA2AFLT3GSK3BALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed