SCHEMBL23401684

SCHEMBL23401684

CCc1cn(-c2ccccc2C)nc1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 2/20 0.42
ADORA2A P29274 1/20 0.40
RXRA P19793 2/20 0.39
GRIN1 Q05586 2/20 0.39
GRIN2B Q13224 2/20 0.39
ELANE P08246 1/20 0.38
FLT3 P36888 1/20 0.38
GSK3B P49841 1/20 0.38
APLNR P35414 1/20 0.36
ALDH1A1 P00352 2/20 0.36
MGLL Q99685 2/20 0.36
TSHR P16473 1/20 0.36
LMNA P02545 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
HSD11B1 P28845 1/20 0.35
HTT P42858 1/20 0.34
KMT2A Q03164 1/20 0.34
MAPK14 Q16539 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23398420 0.89 ADORA3 (0.39) ADORA3ADORA2ARXRAGRIN1GRIN2B
SCHEMBL23399771 0.86 POLB (0.38) ADORA3ADORA2ARXRAGRIN1GRIN2B
SCHEMBL23402912 0.83 GABRA1 (0.39) ADORA3ADORA2ARXRAGRIN1GRIN2B
SCHEMBL23399059 0.83 ADORA3 (0.45) ADORA3ADORA2ARXRAGRIN1GRIN2B
SCHEMBL23403486 0.78 KDM4E (0.50) ADORA3ALDH1A1LMNAL3MBTL1NPC1
SCHEMBL23403407 0.77 ADORA3 (0.40) ADORA3ADORA2ARXRAGRIN1GRIN2B
SCHEMBL28947953 0.77 ADORA3 (0.41) ADORA3ADORA2ARXRAGRIN1GRIN2B
SCHEMBL23403679 0.77 ADORA3 (0.41) ADORA3ADORA2ARXRAGRIN1GRIN2B
SCHEMBL23399006 0.74 GABRA1 (0.41) ADORA3ADORA2ARXRAGRIN1GRIN2B
SCHEMBL23401239 0.74 HSP90AA1 (0.42) ADORA3ADORA2AFLT3GSK3BALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed