SCHEMBL23399015

SCHEMBL23399015

CC(C)c1nn(-c2ccccc2)c(O)c1C(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
GAA P10253 1/20 0.44
MAPK13 O15264 1/20 0.40
MAPK12 P53778 1/20 0.40
MAPK11 Q15759 1/20 0.40
MAPK14 Q16539 1/20 0.40
LMNA P02545 2/20 0.39
NPSR1 Q6W5P4 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
KCNJ6 P48051 4/20 0.37
KCNJ5 P48544 4/20 0.37
KCNJ3 P48549 4/20 0.37
KDM4C Q9H3R0 1/20 0.37
RIPK1 Q13546 2/20 0.36
P2RX7 Q99572 1/20 0.36
PPARA Q07869 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
CYP1A2 P05177 1/20 0.35
MAPK1 P28482 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23398710 0.85 ALDH1A1 (0.37) ALDH1A1MAPK14LMNATDP1KCNJ6
SCHEMBL23400546 0.83 ALDH1A1 (0.44) ALDH1A1GAAMAPK13MAPK12MAPK11
SCHEMBL23399794 0.83 LMNA (0.52) ALDH1A1GAALMNANPSR1TDP1
SCHEMBL23400781 0.83 ALDH1A1 (0.44) ALDH1A1GAAMAPK13MAPK12MAPK11
SCHEMBL23399870 0.80 NPC1 (0.44) ALDH1A1GAAMAPK13MAPK12MAPK11
SCHEMBL23402180 0.80 MEN1 (0.48) ALDH1A1GAAMAPK13MAPK12MAPK11
SCHEMBL23399322 0.79 GCGR (0.42) ALDH1A1GAAMAPK13MAPK12MAPK11
SCHEMBL23400809 0.79 ATM (0.43) ALDH1A1GAAMAPK13MAPK12MAPK11
SCHEMBL23399034 0.79 ALDH1A1 (0.41) ALDH1A1GAAMAPK13MAPK12MAPK11
SCHEMBL23403593 0.79 ALDH1A1 (0.38) ALDH1A1MAPK14LMNASMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed