Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ESRRA | P11474 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23401154 | 0.85 | MAPT (0.62) | MAPTCDK8ACVR1POLBLMNA | |
| SCHEMBL17295117 | 0.84 | MAPT (0.41) | MAPTCDK8ACVR1POLBHTR7 | |
| SCHEMBL17290531 | 0.84 | MAPT (0.41) | MAPTCDK8ACVR1POLBHTR7 | |
| SCHEMBL23400422 | 0.83 | MAPK14 (0.40) | MAPTPOLBLMNAESRRAKMT2A | |
| SCHEMBL23399022 | 0.82 | HEXA (0.44) | MAPTPOLBLMNAPKMESRRA | |
| SCHEMBL6289610 | 0.81 | USP7 (0.39) | MAPTCDK8ACVR1POLBLMNA | |
| SCHEMBL12944870 | 0.80 | MAPT (0.47) | MAPTCDK8ACVR1POLBHTR7 | |
| SCHEMBL23400427 | 0.79 | LMNA (0.33) | MAPTPOLBLMNAESRRARAB9A | |
| SCHEMBL23402413 | 0.79 | GCGR (0.40) | MAPTLMNAESRRAKMT2AMEN1 | |
| SCHEMBL22143978 | 0.79 | MAPT (0.48) | MAPTPOLBLMNAPKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3828159-A1 | STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS | BASF SE (DE) | 2021-06-02 | — | — | EP | disclosed |