Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | CDK8 | P49336 | 1/20 | 0.56 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 8/20 | 0.46 |
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23399050 | 0.85 | MAPT (0.44) | MAPTCDK8ACVR1NPC1RAB9A | |
| SCHEMBL17290362 | 0.81 | TP53 (0.51) | MAPTCDK8SMN1; SMN2KDM4ETP53 | |
| SCHEMBL23398997 | 0.80 | DHFR (0.42) | MAPTCDK8ACVR1NPC1RAB9A | |
| SCHEMBL17295117 | 0.80 | MAPT (0.41) | MAPTCDK8ACVR1NPC1RAB9A | |
| SCHEMBL17290531 | 0.80 | MAPT (0.41) | MAPTCDK8ACVR1NPC1RAB9A | |
| SCHEMBL20320421 | 0.80 | MAPT (0.67) | MAPTCDK8ACVR1NPC1RAB9A | |
| SCHEMBL17290590 | 0.80 | NR1H4 (0.51) | MAPTCDK8ACVR1NPC1RAB9A | |
| SCHEMBL17290370 | 0.78 | PDE1A (0.47) | MAPTCDK8ACVR1NPC1RAB9A | |
| SCHEMBL14132909 | 0.78 | SMN1; SMN2 (0.65) | MAPTNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL23398491 | 0.78 | GAA (0.48) | MAPTCDK8ACVR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3828159-A1 | STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS | BASF SE (DE) | 2021-06-02 | — | — | EP | disclosed |