Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 6/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | COMT | P21964 | 1/20 | 0.36 |
| ▸ | ESRRA | P11474 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | USP7 | Q93009 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23402261 | 0.82 | HIF1A (0.42) | PDE2APRMT5WDR77COMTKDM4E | |
| SCHEMBL14996666 | 0.80 | PDE2A (0.41) | PDE2APRMT5WDR77CYP11B2NPC1 | |
| SCHEMBL23400529 | 0.79 | PRMT5 (0.43) | PRMT5WDR77COMTACHEKDM4E | |
| SCHEMBL23398906 | 0.78 | PTGS2 (0.50) | PTGS2NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL23398811 | 0.78 | ESR1 (0.39) | PDE2ANPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL11971246 | 0.77 | PDE2A (0.39) | PDE2APRMT5WDR77CYP11B2NPC1 | |
| SCHEMBL2522556 | 0.77 | PRMT5 (0.41) | PDE2APRMT5WDR77ACHEPTGS2 | |
| SCHEMBL23087698 | 0.77 | NPC1 (0.41) | PDE2APRMT5WDR77PTGS2CYP11B2 | |
| SCHEMBL23399203 | 0.77 | HTR2B (0.41) | COMTACHEPTGS2USP7KDM4E | |
| SCHEMBL23402446 | 0.77 | HPGD (0.35) | COMTACHEPTGS2USP7KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3828159-A1 | STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS | BASF SE (DE) | 2021-06-02 | — | — | EP | disclosed |