SCHEMBL23399203

SCHEMBL23399203

Cc1ccc(-c2c(O)cnn2C(C)C)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2B P41595 2/20 0.41
HTR2A P28223 1/20 0.41
HTR2C P28335 1/20 0.41
COMT P21964 1/20 0.33
FPR1 P21462 1/20 0.33
PDE9A O76083 1/20 0.33
DGAT1 O75907 1/20 0.33
DRD2 P14416 1/20 0.33
DRD4 P21917 1/20 0.33
ALDH1A1 P00352 2/20 0.32
HTT P42858 1/20 0.32
PTGS2 P35354 1/20 0.32
KDM4E B2RXH2 1/20 0.32
NPC1 O15118 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
USP7 Q93009 1/20 0.32
RET P07949 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23399704 0.84 HTR2A (0.40) HTR2BHTR2AHTR2CALDH1A1PTGS2
SCHEMBL23400778 0.81 SRC (0.40) ALDH1A1KDM4ENPC1HPGDRAB9A
SCHEMBL23399294 0.77 PDE2A (0.39) COMTALDH1A1PTGS2KDM4ENPC1
SCHEMBL23401600 0.76 NPC1 (0.40) HTR2BHTR2AHTR2CCOMTFPR1
SCHEMBL23402614 0.76 HTR2A (0.38) HTR2BHTR2AHTR2CPDE9AALDH1A1
SCHEMBL23398906 0.74 PTGS2 (0.50) ALDH1A1HTTPTGS2NPC1MAPT
SCHEMBL23403361 0.72 CYP11B2 (0.40) COMTDRD2DRD4ALDH1A1HTT
SCHEMBL23402446 0.72 HPGD (0.35) COMTALDH1A1HTTPTGS2KDM4E
SCHEMBL23402548 0.72 HTR2A (0.48) HTR2BHTR2AHTR2CUSP7RET
SCHEMBL23399661 0.71 CYP1A2 (0.33) HTR2BHTR2AHTR2CDRD2DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed