SCHEMBL23399404

SCHEMBL23399404

Cc1cccc(-c2nn(-c3ccccc3)c(O)c2C)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
NPC1 O15118 3/20 0.52
RAB9A P51151 3/20 0.52
L3MBTL1 Q9Y468 3/20 0.52
NFKB1 P19838 1/20 0.52
NFKB2 Q00653 1/20 0.52
RELA Q04206 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
KMT2A Q03164 4/20 0.48
RPA1 P27694 1/20 0.46
LMNA P02545 2/20 0.45
MAPT P10636 6/20 0.44
TP53 P04637 3/20 0.44
MEN1 O00255 3/20 0.44
GRM5 P41594 1/20 0.43
THRB P10828 1/20 0.43
KCNJ6 P48051 1/20 0.41
KCNJ5 P48544 1/20 0.41
KCNJ3 P48549 1/20 0.41
GLA P06280 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23403301 0.93 ALDH1A1 (0.51) ALDH1A1NPC1RAB9AL3MBTL1NFKB1
SCHEMBL23402921 0.91 L3MBTL1 (0.52) ALDH1A1NPC1RAB9AL3MBTL1NFKB1
SCHEMBL23399853 0.91 RPA1 (0.52) ALDH1A1NPC1RAB9AL3MBTL1NFKB1
SCHEMBL23402010 0.88 NPC1 (0.52) ALDH1A1NPC1RAB9AL3MBTL1NFKB1
SCHEMBL23402267 0.88 MEN1 (0.55) ALDH1A1NPC1RAB9ASMN1; SMN2KMT2A
SCHEMBL23400863 0.85 NPC1 (0.49) ALDH1A1NPC1RAB9AL3MBTL1NFKB1
SCHEMBL23401228 0.85 CA1 (0.44) ALDH1A1NPC1RAB9AL3MBTL1NFKB1
SCHEMBL23402685 0.84 RPA1 (0.51) ALDH1A1NPC1RAB9AL3MBTL1NFKB1
SCHEMBL23400133 0.83 CDK2 (0.50) ALDH1A1NPC1RAB9ASMN1; SMN2KMT2A
SCHEMBL23402995 0.83 MEN1 (0.48) ALDH1A1NPC1RAB9ASMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed