SCHEMBL23399655

SCHEMBL23399655

CCCCc1cc(O)nn1C(C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.34
MAPK1 P28482 2/20 0.34
RAB9A P51151 2/20 0.34
HPGD P15428 2/20 0.34
HTT P42858 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
GPR84 Q9NQS5 6/20 0.34
DHFR P00374 1/20 0.33
TYR P14679 1/20 0.33
HCAR3 P49019 1/20 0.32
HCAR2 Q8TDS4 1/20 0.32
PTGS2 P35354 3/20 0.32
CYP3A4 P08684 1/20 0.32
KDM4E B2RXH2 2/20 0.31
GGPS1 O95749 1/20 0.31
KDM5A P29375 1/20 0.31
KDM5B Q9UGL1 1/20 0.31
TP53 P04637 1/20 0.31
POLB P06746 1/20 0.31
NFKB1 P19838 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23403336 0.89 GAA (0.30)
SCHEMBL23399360 0.82 GAA (0.31)
SCHEMBL23400692 0.77 GPR84 (0.40) NPC1MAPK1RAB9AHPGDHTT
SCHEMBL23399833 0.75 NPC1 (0.36) NPC1MAPK1RAB9AHPGDHTT
SCHEMBL1232533 0.74 KMT2A (0.40) KDM4ETP53POLB
SCHEMBL23403278 0.74 GABRA1 (0.30)
SCHEMBL23398867 0.74 GPR84 (0.38) NPC1MAPK1RAB9AHPGDHTT
SCHEMBL23403308 0.74 ESR1 (0.38) NPC1MAPK1RAB9AHPGDHTT
SCHEMBL23402451 0.72 NPC1 (0.34) NPC1MAPK1RAB9AHPGDHTT
SCHEMBL23402884 0.72 TLR7 (0.35) NPC1MAPK1RAB9AHPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed