SCHEMBL23399733

SCHEMBL23399733

CCCc1c(-c2ccccc2)c(O)nn1-c1ccc(OC)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
MAPT P10636 2/20 0.46
RPA1 P27694 1/20 0.45
RAB9A P51151 2/20 0.44
NPC1 O15118 1/20 0.44
POLB P06746 1/20 0.44
HPGD P15428 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
MEN1 O00255 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
KMT2A Q03164 1/20 0.43
HSD11B1 P28845 1/20 0.40
RXRA P19793 1/20 0.39
RXRB P28702 1/20 0.39
RXRG P48443 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23398656 0.93 RPA1 (0.44) ALDH1A1MAPTRPA1RAB9ANPC1
SCHEMBL23403399 0.90 RPA1 (0.47) ALDH1A1RPA1RAB9ANPC1POLB
SCHEMBL23401243 0.89 PTGS1 (0.42) RAB9ANPC1POLBHPGDSMN1; SMN2
SCHEMBL23399550 0.88 USP2 (0.44) ALDH1A1MAPTRAB9ANPC1POLB
SCHEMBL23398626 0.86 MAPT (0.41) ALDH1A1MAPTRAB9ANPC1HPGD
SCHEMBL23402113 0.84 RPA1 (0.44) ALDH1A1RPA1RAB9ANPC1POLB
SCHEMBL23403223 0.82 PTGS2 (0.46) ALDH1A1MAPTRPA1RAB9ANPC1
SCHEMBL23398540 0.81 MAPT (0.44) ALDH1A1MAPTRAB9ANPC1POLB
SCHEMBL23402897 0.80 RAB9A (0.52) MAPTRPA1RAB9ANPC1POLB
SCHEMBL23403272 0.80 CNR1 (0.47) ALDH1A1MAPTRAB9ANPC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed