SCHEMBL23399862

SCHEMBL23399862

Cc1ccc(-c2c(C)nn(C(C)C)c2O)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.39
HTR2C P28335 1/20 0.39
HTR2B P41595 1/20 0.39
RET P07949 1/20 0.34
PDE1A P54750 1/20 0.34
PDE1B Q01064 1/20 0.34
PDE1C Q14123 1/20 0.34
ESR1 P03372 1/20 0.34
FPR1 P21462 2/20 0.34
KMT2A Q03164 2/20 0.33
NPC1 O15118 2/20 0.33
TP53 P04637 2/20 0.33
MAPT P10636 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
ACHE P22303 2/20 0.33
BCHE P06276 1/20 0.33
LIPE Q05469 1/20 0.33
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23399190 0.84 SRC (0.40) HTR2AHTR2CHTR2BRETESR1
SCHEMBL23403240 0.83 HEXA (0.42) HTR2AHTR2CHTR2BRETFPR1
SCHEMBL23400548 0.83 GCGR (0.40) HTR2AHTR2CHTR2BRETESR1
SCHEMBL23398571 0.79 TDP1 (0.44) PDE1APDE1BPDE1CESR1KMT2A
SCHEMBL23403688 0.79 DPP4 (0.42) HTR2AHTR2CHTR2BDPP4DPP8
SCHEMBL23399335 0.79 TDP1 (0.44) PDE1APDE1BPDE1CESR1KMT2A
SCHEMBL23399050 0.78 MAPT (0.44) KMT2ANPC1TP53MAPTRAB9A
SCHEMBL23398499 0.77 HTR2A (0.38) HTR2AHTR2CHTR2BRETPDE1A
SCHEMBL23398924 0.77 HTR2A (0.48) HTR2AHTR2CHTR2BRETPDE1A
SCHEMBL23400953 0.76 HTR2A (0.47) HTR2AHTR2CHTR2BRETKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed