SCHEMBL23400784

SCHEMBL23400784

CC(C)Cn1ncc(-c2ccccc2)c1O

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTGIR P43119 2/20 0.46
S1PR1 P21453 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.41
CNR2 P34972 2/20 0.40
MAPK1 P28482 1/20 0.39
TRPV1 Q8NER1 2/20 0.38
ALDH1A1 P00352 2/20 0.37
HPGD P15428 1/20 0.37
BCL2L1 Q07817 1/20 0.37
HSD17B10 Q99714 1/20 0.37
LPAR1 Q92633 1/20 0.36
PDE9A O76083 3/20 0.36
CACNA1B Q00975 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
CNR1 P21554 1/20 0.35
AHR P35869 1/20 0.35
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23401453 0.86 P2RX3 (0.37) PTGIRS1PR1ALDH1A1HPGDPDE9A
SCHEMBL23399467 0.84 KMT2A (0.43) S1PR1SMN1; SMN2CNR2ALDH1A1NPC1
SCHEMBL23401836 0.81 SMN1; SMN2 (0.47) PTGIRSMN1; SMN2MAPK1ALDH1A1HPGD
SCHEMBL23398900 0.81 MAPT (0.36) PTGIRS1PR1SMN1; SMN2MAPK1HPGD
SCHEMBL23402355 0.79 PTGIR (0.47) PTGIRSMN1; SMN2MAPK1ALDH1A1HPGD
SCHEMBL23400063 0.77 S1PR1 (0.46) PTGIRS1PR1SMN1; SMN2CNR2MAPK1
SCHEMBL23398618 0.76 PTGIR (0.51) PTGIRSMN1; SMN2ALDH1A1
SCHEMBL23401005 0.75 RAB9A (0.39) PTGIRSMN1; SMN2MAPK1ALDH1A1HPGD
SCHEMBL23400268 0.72 CREBBP (0.45) PTGIRSMN1; SMN2MAPK1ALDH1A1HPGD
SCHEMBL23403139 0.72 HTR2A (0.37) SMN1; SMN2PDE9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed