SCHEMBL23401121

SCHEMBL23401121

CCCCn1nc(-c2ccccc2C)c(CC(C)C)c1O

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.37
TLR8 Q9NR97 1/20 0.37
NR1H3 Q13133 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
CYP1A2 P05177 1/20 0.35
MAPT P10636 1/20 0.35
CNR2 P34972 2/20 0.35
PDE4A P27815 2/20 0.34
PDE4B Q07343 2/20 0.34
PDE4C Q08493 2/20 0.34
PDE4D Q08499 2/20 0.34
PDE3B Q13370 2/20 0.34
PDE3A Q14432 2/20 0.34
GCGR P47871 1/20 0.33
ALPL P05186 1/20 0.33
ALPG P10696 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23400274 0.93 ESR1 (0.41) ESR1TLR8MEN1KMT2ACYP1A2
SCHEMBL23401357 0.87 ESR1 (0.40) ESR1TLR8NR1H3MEN1KMT2A
SCHEMBL23398519 0.87 TRPM8 (0.34) ESR1MEN1KMT2ACYP1A2MAPT
SCHEMBL23402165 0.87 ESR1 (0.40) ESR1TLR8NR1H3MEN1KMT2A
SCHEMBL23399093 0.86 ESR1 (0.39) ESR1TLR8NR1H3MEN1KMT2A
SCHEMBL23401610 0.85 GABRA1 (0.33) MAPTCNR2
SCHEMBL23403080 0.84 MEN1 (0.48) ESR1NR1H3MEN1KMT2ACYP1A2
SCHEMBL23399522 0.82 ESR1 (0.38) ESR1TLR8NR1H3MEN1KMT2A
SCHEMBL23401012 0.82 ESR1 (0.42) ESR1TLR8MEN1KMT2AMAPT
SCHEMBL23401792 0.82 ESR1 (0.41) ESR1TLR8NR1H3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed