SCHEMBL23401151

SCHEMBL23401151

CCc1c(NC=O)c(=O)n(C)n1-c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 3/20 0.44
SMN1; SMN2 Q16637 1/20 0.42
POLB P06746 1/20 0.42
PTGS2 P35354 2/20 0.41
BCHE P06276 1/20 0.41
KDM4E B2RXH2 2/20 0.41
TSHR P16473 1/20 0.41
GAA P10253 6/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
PKM P14618 1/20 0.39
KMT2A Q03164 1/20 0.39
ALDH1A1 P00352 4/20 0.39
LMNA P02545 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ALOX15 P16050 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23400672 0.88 ALDH1A1 (0.43) FPR2SMN1; SMN2PTGS2KDM4ETSHR
SCHEMBL23401217 0.85 FPR2 (0.39) FPR2SMN1; SMN2POLBPTGS2KDM4E
SCHEMBL23401644 0.84 FPR2 (0.38) FPR2SMN1; SMN2POLBPTGS2KDM4E
SCHEMBL23400334 0.83 KMT2A (0.38) FPR2SMN1; SMN2POLBTSHRGAA
SCHEMBL23402932 0.82 FPR2 (0.37) FPR2SMN1; SMN2PTGS2KDM4ETSHR
SCHEMBL23402763 0.82 ALDH1A1 (0.41) FPR2SMN1; SMN2POLBKDM4ETSHR
SCHEMBL23402195 0.82 FPR2 (0.39) FPR2SMN1; SMN2POLBPTGS2KDM4E
SCHEMBL23402588 0.81 ALDH1A1 (0.39) FPR2SMN1; SMN2KDM4ETSHRGAA
SCHEMBL23399779 0.81 BCHE (0.51) SMN1; SMN2PTGS2BCHEKDM4ETSHR
SCHEMBL8654712 0.79 TSHR (0.49) FPR2SMN1; SMN2PTGS2KDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed