SCHEMBL23401283

SCHEMBL23401283

CCCCn1nc(O)cc1-c1ccc(C)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMPD1 P17405 6/20 0.43
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
NR1H3 Q13133 1/20 0.39
HDAC3 O15379 2/20 0.38
HDAC4 P56524 2/20 0.38
HDAC1 Q13547 2/20 0.38
HDAC7 Q8WUI4 2/20 0.38
HDAC2 Q92769 2/20 0.38
HDAC10 Q969S8 2/20 0.38
HDAC11 Q96DB2 2/20 0.38
HDAC8 Q9BY41 2/20 0.38
HDAC6 Q9UBN7 2/20 0.38
HDAC9 Q9UKV0 2/20 0.38
HDAC5 Q9UQL6 2/20 0.38
NCOR2 Q9Y618 2/20 0.38
CNR1 P21554 2/20 0.38
ESR1 P03372 2/20 0.38
NPC1 O15118 1/20 0.38
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23403306 0.91 ADORA2A (0.41) SMPD1MEN1KMT2AHDAC3HDAC4
SCHEMBL23401343 0.86 SMPD1 (0.55) SMPD1MEN1KMT2ANR1H3CNR1
SCHEMBL23401468 0.84 TP53 (0.43) SMPD1MEN1KMT2ANR1H3CNR1
SCHEMBL23401663 0.84 HDAC3 (0.41) MEN1KMT2AHDAC3HDAC4HDAC1
SCHEMBL23399351 0.77 NR1H2 (0.43) MEN1KMT2AHDAC3HDAC4HDAC1
SCHEMBL23402491 0.77 SMPD1 (0.41) SMPD1NR1H3CNR1ESR1TLR8
SCHEMBL23400225 0.76 SMPD1 (0.48) SMPD1MEN1KMT2ANR1H3CNR1
SCHEMBL23402917 0.76 HSD11B1 (0.43) ESR1NPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL23399968 0.75 ESRRA (0.45) SMPD1MEN1KMT2AHDAC3HDAC4
SCHEMBL23403285 0.75 KDM4E (0.45) MEN1KMT2ANR1H3CNR1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed