SCHEMBL23401323

SCHEMBL23401323

CCCc1c(O)nn(CC(C)C)c1-c1ccc(C)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.39
ESR1 P03372 2/20 0.39
CYP2C9 P11712 2/20 0.39
MAPT P10636 2/20 0.39
CYP2C19 P33261 2/20 0.39
KDM4E B2RXH2 1/20 0.39
GMNN O75496 1/20 0.39
USP2 O75604 1/20 0.39
LMNA P02545 1/20 0.39
TP53 P04637 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39
ALOX12 P18054 1/20 0.39
NFKB1 P19838 1/20 0.39
MAPK1 P28482 1/20 0.39
THPO P40225 1/20 0.39
BLM P54132 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23403169 0.93 GCGR (0.39) KMT2AESR1CYP2C9MAPTCYP2C19
SCHEMBL23403072 0.89 USP7 (0.34) KMT2AMAPTCYP2C19KDM4ETP53
SCHEMBL23398557 0.88 ALDH1A1 (0.37) KMT2AESR1CYP2C9MAPTCYP2C19
SCHEMBL23403302 0.86 DPP4 (0.33) KMT2AMAPTCYP2C19KDM4EUSP2
SCHEMBL23398551 0.86 MAPT (0.43) KMT2AESR1CYP2C9MAPTCYP2C19
SCHEMBL23403007 0.85 CTSS (0.38) KMT2AMAPTLMNATP53MAPK1
SCHEMBL23400593 0.85 ESR1 (0.42) KMT2AESR1CYP2C9MAPTCYP2C19
SCHEMBL23402271 0.82 MAPT (0.35) KMT2AESR1CYP2C9MAPTCYP2C19
SCHEMBL23402454 0.82 KMT2A (0.40) KMT2AESR1CYP2C9MAPTCYP2C19
SCHEMBL23401131 0.81 MEN1 (0.34) KMT2AMAPTCYP2C19MEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed