Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23400590 | 1.00 | TDP1 (0.51) | TDP1SMN1; SMN2POLBLMNAL3MBTL1 | |
| SCHEMBL23400489 | 0.93 | SMN1; SMN2 (0.40) | TDP1SMN1; SMN2POLBLMNAL3MBTL1 | |
| SCHEMBL11674731 | 0.91 | MEN1 (0.50) | TDP1SMN1; SMN2POLBLMNAMAPT | |
| SCHEMBL23403201 | 0.86 | TGFBR1 (0.42) | TDP1SMN1; SMN2POLBLMNAL3MBTL1 | |
| SCHEMBL28003111 | 0.85 | CA1 (0.61) | SMN1; SMN2POLBL3MBTL1MAPTCA1 | |
| SCHEMBL30639609 | 0.85 | KDM4E (0.50) | TDP1SMN1; SMN2LMNAL3MBTL1MAPT | |
| SCHEMBL23400259 | 0.84 | KMT2A (0.42) | SMN1; SMN2POLBL3MBTL1MAPTCA1 | |
| SCHEMBL23399393 | 0.83 | MEN1 (0.50) | TDP1SMN1; SMN2POLBMAPTMEN1 | |
| SCHEMBL23402086 | 0.83 | CCNA2 (0.48) | TDP1SMN1; SMN2LMNAMAPTCA1 | |
| SCHEMBL23401685 | 0.83 | MAPT (0.46) | TDP1SMN1; SMN2POLBLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3828159-A1 | STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS | BASF SE (DE) | 2021-06-02 | — | — | EP | disclosed |