SCHEMBL23401577

SCHEMBL23401577

Cc1ccccc1-c1nn(C(C)C)c(O)c1C(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.38
LDHA P00338 1/20 0.37
PIK3CD O00329 3/20 0.37
ABL1 P00519 3/20 0.37
EGFR P00533 3/20 0.37
HCK P08631 3/20 0.37
SRC P12931 3/20 0.37
KDR P35968 3/20 0.37
PIK3CA P42336 3/20 0.37
PIK3CB P42338 3/20 0.37
MTOR P42345 3/20 0.37
PIK3CG P48736 3/20 0.37
EPHB4 P54760 3/20 0.37
PRKDC P78527 3/20 0.37
PI4KB Q9UBF8 3/20 0.37
RAB9A P51151 6/20 0.36
SMN1; SMN2 Q16637 6/20 0.36
NPC1 O15118 5/20 0.36
CASP3 P42574 1/20 0.36
SENP8 Q96LD8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23400556 0.84 LDHA (0.37) LDHARAB9ASMN1; SMN2NPC1CASP3
SCHEMBL23399273 0.84 ESR1 (0.40) ESR1LDHAPIK3CDABL1EGFR
SCHEMBL23400577 0.81 DCTPP1 (0.39) LDHAMAPTTSHRUSP2ALDH1A1
SCHEMBL23399664 0.81 LDHA (0.35) ESR1LDHAPIK3CDRAB9ASMN1; SMN2
SCHEMBL23399533 0.81 HSP90AA1 (0.36) LDHARAB9ASMN1; SMN2CASP3SENP8
SCHEMBL23402022 0.81 LDHA (0.35) LDHAABL1SRCRAB9ASMN1; SMN2
SCHEMBL23398750 0.80 LDHA (0.34) ESR1LDHAPIK3CDPIK3CGRAB9A
SCHEMBL31617674 0.79 ESR1 (0.39) ESR1LDHAPIK3CDABL1EGFR
SCHEMBL23398508 0.79 ESR1 (0.42) ESR1LDHAPIK3CDABL1EGFR
SCHEMBL23402497 0.79 ESR1 (0.37) ESR1PIK3CDABL1EGFRHCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed