SCHEMBL23401593

SCHEMBL23401593

CCCCc1c(-c2ccccc2)nn(-c2ccccc2C)c1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
TSHR P16473 3/20 0.40
HSD11B1 P28845 1/20 0.39
ESR1 P03372 2/20 0.39
KDM4E B2RXH2 1/20 0.39
GMNN O75496 1/20 0.39
USP2 O75604 1/20 0.39
LMNA P02545 1/20 0.39
TP53 P04637 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
MAPT P10636 1/20 0.39
CYP2C9 P11712 1/20 0.39
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39
NFKB1 P19838 1/20 0.39
MAPK1 P28482 1/20 0.39
CYP2C19 P33261 1/20 0.39
THPO P40225 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23401492 0.93 MAPT (0.45) ALDH1A1TSHRHSD11B1ESR1KDM4E
SCHEMBL23399363 0.92 ADORA3 (0.40) ALDH1A1TSHRHSD11B1ESR1KDM4E
SCHEMBL23399821 0.89 ALDH1A1 (0.38) ALDH1A1TSHRKDM4ETP53MAPT
SCHEMBL23403221 0.88 ALDH1A1 (0.45) ALDH1A1TSHRESR1KDM4EMAPT
SCHEMBL23401320 0.87 TLR8 (0.36) ALDH1A1HSD11B1USP2TP53MAPT
SCHEMBL23402388 0.86 MAPT (0.46) ALDH1A1TSHRESR1KDM4EGMNN
SCHEMBL23399624 0.85 KMT2A (0.47) ALDH1A1TSHRHSD11B1ESR1KDM4E
SCHEMBL23402728 0.83 POLB (0.38) ALDH1A1TSHRHSD11B1KDM4ELMNA
SCHEMBL23399272 0.83 ALDH1A1 (0.41) ALDH1A1TSHRHSD11B1ESR1GPR84
SCHEMBL23400568 0.82 DHODH (0.38) ALDH1A1TSHRHSD11B1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed