SCHEMBL23401797

SCHEMBL23401797

CCc1nn(C(C)(C)C)c(O)c1-c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.45
HPGD P15428 2/20 0.45
DHFR P00374 1/20 0.40
HEXA P06865 1/20 0.40
HEXB P07686 1/20 0.40
MAPT P10636 3/20 0.38
KDM4E B2RXH2 3/20 0.37
ESR1 P03372 2/20 0.37
ESR2 Q92731 2/20 0.37
RCE1 Q9Y256 1/20 0.37
GCGR P47871 1/20 0.37
ALDH1A1 P00352 3/20 0.35
MAPK1 P28482 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
GAA P10253 2/20 0.35
PTGS1 P23219 1/20 0.34
PTGS2 P35354 1/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23399302 0.88 SMN1; SMN2 (0.43) SMN1; SMN2HPGDDHFRMAPTKDM4E
SCHEMBL23403137 0.86 HEXA (0.41) SMN1; SMN2HPGDHEXAHEXBMAPT
SCHEMBL23399675 0.85 HPGD (0.41) SMN1; SMN2HPGDDHFRMAPTKDM4E
SCHEMBL23401530 0.82 SMN1; SMN2 (0.66) SMN1; SMN2HPGDMAPTKDM4EALDH1A1
SCHEMBL23398516 0.79 ALDH1A1 (0.49) SMN1; SMN2DHFRHEXAHEXBMAPT
SCHEMBL23400097 0.79 SMN1; SMN2 (0.49) SMN1; SMN2HPGDESR1ESR2ALDH1A1
SCHEMBL23398997 0.79 DHFR (0.42) DHFRHEXAHEXBMAPTKDM4E
SCHEMBL23400098 0.78 HTR2A (0.43) SMN1; SMN2HPGDDHFRHEXAHEXB
SCHEMBL23399319 0.78 DHFR (0.45) SMN1; SMN2DHFRHEXAHEXBMAPT
SCHEMBL23403326 0.78 SMN1; SMN2 (0.47) SMN1; SMN2HPGDMAPTKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed