SCHEMBL23401982

SCHEMBL23401982

CCCCc1c(-c2cccc(C)c2)nn(-c2ccccc2)c1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
ALDH1A1 P00352 2/20 0.45
NFKB1 P19838 2/20 0.45
NFKB2 Q00653 1/20 0.45
RELA Q04206 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
CNR1 P21554 1/20 0.44
CNR2 P34972 1/20 0.44
TP53 P04637 5/20 0.43
KMT2A Q03164 3/20 0.41
SOAT2 O75908 4/20 0.41
SOAT1 P35610 4/20 0.41
ADORA3 P0DMS8 2/20 0.40
LMNA P02545 2/20 0.40
RPA1 P27694 1/20 0.40
MAPT P10636 4/20 0.39
ADORA2A P29274 1/20 0.39
MEN1 O00255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23400291 0.94 ALDH1A1 (0.44) NPC1RAB9AALDH1A1NFKB1NFKB2
SCHEMBL23401939 0.94 ALDH1A1 (0.46) NPC1RAB9AALDH1A1NFKB1NFKB2
SCHEMBL23402787 0.93 RPA1 (0.45) NPC1RAB9AALDH1A1NFKB1NFKB2
SCHEMBL23402799 0.93 KMT2A (0.45) NPC1RAB9AALDH1A1NFKB1NFKB2
SCHEMBL23399624 0.90 KMT2A (0.47) NPC1RAB9AALDH1A1NFKB1SMN1; SMN2
SCHEMBL23402257 0.89 ALDH1A1 (0.48) NPC1RAB9AALDH1A1NFKB1NFKB2
SCHEMBL23402179 0.88 ALDH1A1 (0.45) NPC1RAB9AALDH1A1NFKB1NFKB2
SCHEMBL23398568 0.87 CA1 (0.40) ALDH1A1NFKB1L3MBTL1TP53KMT2A
SCHEMBL23398643 0.86 RPA1 (0.46) NPC1RAB9AALDH1A1NFKB1NFKB2
SCHEMBL23402343 0.86 KMT2A (0.47) NPC1RAB9ANFKB1SMN1; SMN2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed