SCHEMBL23398643

SCHEMBL23398643

CCCc1c(-c2ccccc2)nn(-c2cccc(C)c2)c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RPA1 P27694 1/20 0.46
KMT2A Q03164 4/20 0.45
KDM4E B2RXH2 3/20 0.45
TP53 P04637 3/20 0.45
MAPT P10636 3/20 0.45
NFKB1 P19838 2/20 0.45
LMNA P02545 2/20 0.45
USP2 O75604 2/20 0.45
GMNN O75496 1/20 0.45
ESR1 P03372 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
ALOX15 P16050 1/20 0.45
TSHR P16473 1/20 0.45
ALOX12 P18054 1/20 0.45
MAPK1 P28482 1/20 0.45
CYP2C19 P33261 1/20 0.45
THPO P40225 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23402787 0.94 RPA1 (0.45) RPA1KMT2AKDM4ETP53MAPT
SCHEMBL23402179 0.94 ALDH1A1 (0.45) RPA1KMT2AKDM4ETP53MAPT
SCHEMBL23401939 0.93 ALDH1A1 (0.46) RPA1KMT2AKDM4ETP53MAPT
SCHEMBL23402239 0.93 KDM4E (0.48) RPA1KMT2AKDM4ETP53MAPT
SCHEMBL23403477 0.90 RPA1 (0.48) RPA1KMT2AKDM4ETP53MAPT
SCHEMBL23401457 0.88 KMT2A (0.56) KMT2AKDM4ETP53MAPTNFKB1
SCHEMBL23400291 0.88 ALDH1A1 (0.44) RPA1KMT2AKDM4ETP53MAPT
SCHEMBL23398560 0.86 LMNA (0.41) RPA1KMT2AKDM4ETP53MAPT
SCHEMBL23401982 0.86 NPC1 (0.45) RPA1KMT2AKDM4ETP53MAPT
SCHEMBL23401043 0.86 KMT2A (0.54) KMT2AKDM4ETP53MAPTNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed