SCHEMBL23402124

SCHEMBL23402124

Cc1cccc(-c2cc(O)n(-c3cccc(C)c3)n2)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.60
NPC1 O15118 4/20 0.60
RAB9A P51151 4/20 0.60
L3MBTL1 Q9Y468 3/20 0.60
SMN1; SMN2 Q16637 2/20 0.60
NFKB1 P19838 1/20 0.60
NFKB2 Q00653 1/20 0.60
RELA Q04206 1/20 0.60
LMNA P02545 2/20 0.51
KDM4E B2RXH2 1/20 0.50
MAPT P10636 3/20 0.49
TP53 P04637 2/20 0.49
RPA1 P27694 1/20 0.49
GRM5 P41594 1/20 0.46
KMT2A Q03164 3/20 0.44
MEN1 O00255 1/20 0.42
IDO1 P14902 1/20 0.41
METAP2 P50579 1/20 0.41
HSP90AA1 P07900 1/20 0.41
MGLL Q99685 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23400587 0.92 ALDH1A1 (0.58) ALDH1A1NPC1RAB9AL3MBTL1SMN1; SMN2
SCHEMBL23398548 0.92 ALDH1A1 (0.71) ALDH1A1NPC1RAB9AL3MBTL1SMN1; SMN2
SCHEMBL23402326 0.89 NPC1 (0.58) ALDH1A1NPC1RAB9AL3MBTL1SMN1; SMN2
SCHEMBL23400645 0.88 L3MBTL1 (0.51) ALDH1A1NPC1RAB9AL3MBTL1SMN1; SMN2
SCHEMBL23401551 0.82 ALDH1A1 (0.51) ALDH1A1NPC1RAB9AL3MBTL1SMN1; SMN2
SCHEMBL23398597 0.80 RPA1 (0.46) ALDH1A1NPC1RAB9AL3MBTL1SMN1; SMN2
SCHEMBL23402778 0.80 NPC1 (0.49) ALDH1A1NPC1RAB9AL3MBTL1SMN1; SMN2
SCHEMBL16864370 0.80 ALDH1A1 (0.49) ALDH1A1NPC1RAB9AL3MBTL1SMN1; SMN2
SCHEMBL23403518 0.80 ALDH1A1 (0.49) ALDH1A1NPC1RAB9AL3MBTL1SMN1; SMN2
SCHEMBL23403503 0.80 ALDH1A1 (0.67) ALDH1A1NPC1RAB9AL3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed