SCHEMBL23402425

SCHEMBL23402425

CCCn1nc(O)cc1-c1cccc(C)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
KMT2A Q03164 1/20 0.42
ESR1 P03372 2/20 0.39
TP53 P04637 1/20 0.39
TLR8 Q9NR97 2/20 0.39
TRPM8 Q7Z2W7 1/20 0.38
CYP11B1 P15538 1/20 0.37
CYP11B2 P19099 1/20 0.37
SLC5A1 P13866 1/20 0.37
SLC16A3 O15427 1/20 0.36
SLC16A1 P53985 1/20 0.36
MCTS1 Q9ULC4 1/20 0.36
SMPD1 P17405 1/20 0.36
CNR2 P34972 1/20 0.36
TSHR P16473 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23401468 0.92 TP53 (0.43) MEN1CYP1A2KMT2AESR1TP53
SCHEMBL23400794 0.88 NPC1 (0.41) MEN1CYP1A2CYP2C9CYP2C19KMT2A
SCHEMBL23400225 0.84 SMPD1 (0.48) MEN1KMT2AESR1SLC5A1SLC16A3
SCHEMBL23403306 0.83 ADORA2A (0.41) MEN1CYP1A2CYP2C9CYP2C19KMT2A
SCHEMBL8517784 0.82 TLR8 (0.44) MEN1CYP1A2CYP2C9CYP2C19KMT2A
SCHEMBL23401693 0.81 NR1H2 (0.43) KMT2ATLR8CYP11B1CYP11B2SLC5A1
SCHEMBL23403010 0.80 TLR8 (0.40) TLR8TSHRRPA1
SCHEMBL23401961 0.77 NPC1 (0.43) MEN1CYP1A2CYP2C9CYP2C19KMT2A
SCHEMBL23400166 0.77 TLR8 (0.44) MEN1CYP1A2CYP2C9CYP2C19KMT2A
SCHEMBL23401343 0.76 SMPD1 (0.55) MEN1CYP1A2CYP2C9CYP2C19KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed