Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23402054 | 0.92 | TLR8 (0.48) | TLR8NPC1RAB9AKDM4ECTSS | |
| SCHEMBL23398474 | 0.88 | NPC1 (0.46) | TLR8NPC1RAB9AKDM4ECTSS | |
| SCHEMBL23402684 | 0.84 | ALDH1A1 (0.46) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL23402249 | 0.83 | SMN1; SMN2 (0.45) | NPC1RAB9AKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL23400239 | 0.81 | NPC1 (0.43) | NPC1RAB9AKDM4ECTSSCTSK | |
| SCHEMBL23402778 | 0.80 | NPC1 (0.49) | TLR8NPC1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL28673217 | 0.78 | FYN (0.50) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL23402425 | 0.77 | MEN1 (0.42) | TLR8MEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23401961 | 0.77 | NPC1 (0.43) | TLR8NPC1RAB9AKDM4ECTSS | |
| SCHEMBL23400340 | 0.76 | NR1H3 (0.50) | TLR8ALDH1A1SMN1; SMN2MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3828159-A1 | STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS | BASF SE (DE) | 2021-06-02 | — | — | EP | disclosed |