Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HEXA | P06865 | 1/20 | 0.40 |
| ▸ | HEXB | P07686 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8373875 | 0.88 | ALDH1A1 (0.43) | TLR8KMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL8375341 | 0.84 | SMPD1 (0.45) | TLR8KMT2AMEN1CYP1A2ALDH1A1 | |
| SCHEMBL8517656 | 0.83 | GAA (0.41) | TLR8KMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL23402425 | 0.82 | MEN1 (0.42) | TLR8KMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL8374724 | 0.82 | MAPT (0.47) | TLR8KMT2ATDP1TP53 | |
| SCHEMBL8038688 | 0.75 | TLR8 (0.43) | TLR8KMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL23401468 | 0.74 | TP53 (0.43) | TLR8KMT2AMEN1CYP1A2TP53 | |
| SCHEMBL8375164 | 0.73 | SMPD1 (0.49) | TLR8KMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL8376298 | 0.73 | SRC (0.49) | TLR8KMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL14750049 | 0.72 | NPC1 (0.61) | KMT2AMEN1CYP1A2CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900206-A1 | NEW DIAMINO PYRAZOLS, THEIR SYNTHESIS, KERATIN FIBRE DYEING COMPOSITIONS CONTAINING THEM, KERATIN FIBRE DYEING METHODS | L'OREAL (FR) | 1999-03-10 | — | — | EP | claimed |
| WO-1997042173-A1 | NEW DIAMINO PYRAZOLS, THEIR SYNTHESIS, KERATIN FIBRE DYEING COMPOSITIONS CONTAINING THEM, KERATIN FIBRE DYEING METHODS | L'OREAL (FR) | 1997-11-13 | — | — | WO | claimed |