SCHEMBL23403136

SCHEMBL23403136

CC(=O)c1nn(-c2ccccc2C)c(-c2ccccc2)c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
POLB P06746 1/20 0.48
TSHR P16473 1/20 0.46
KDM4E B2RXH2 2/20 0.44
ALOX15 P16050 1/20 0.44
HSD17B10 Q99714 1/20 0.44
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
NPSR1 Q6W5P4 1/20 0.41
MAPK14 Q16539 2/20 0.40
MAPK13 O15264 1/20 0.40
MAPK12 P53778 1/20 0.40
MAPK11 Q15759 1/20 0.40
CYP1A2 P05177 3/20 0.40
CYP2C9 P11712 2/20 0.40
CYP2C19 P33261 2/20 0.40
MEN1 O00255 1/20 0.39
RECQL P46063 1/20 0.39
KMT2A Q03164 1/20 0.39
NR1H2 P55055 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14536715 0.90 CNR1 (0.44) ALDH1A1
SCHEMBL23403519 0.83 ADRA1A (0.43) ALDH1A1POLBTSHRNPSR1MAPK14
SCHEMBL23402300 0.82 KDM4E (0.45) ALDH1A1POLBTSHRKDM4EALOX15
SCHEMBL23398702 0.81 ALDH1A1 (0.49) ALDH1A1POLBTSHRKDM4EALOX15
SCHEMBL23400296 0.81 CYP2C9 (0.49) ALDH1A1KDM4ECA1CA2NPSR1
SCHEMBL23400270 0.80 PTGER1 (0.48) ALDH1A1POLBTSHRKDM4EALOX15
SCHEMBL280162 0.76 CSF1R (0.46) ALDH1A1POLBKDM4EHSD17B10CA1
SCHEMBL23403652 0.76 ALDH1A1 (0.45) ALDH1A1POLBTSHRKDM4EALOX15
SCHEMBL23402874 0.76 ALDH1A1 (0.45) ALDH1A1TSHRKDM4EHSD17B10NPSR1
SCHEMBL23400420 0.75 ALDH1A1 (0.50) ALDH1A1POLBTSHRKDM4EALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed