SCHEMBL23403178

SCHEMBL23403178

CCCCc1c(O)nn(C(C)C)c1-c1ccc(C)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.41
HTR2C P28335 1/20 0.41
HTR2B P41595 1/20 0.41
GCGR P47871 3/20 0.40
ADORA3 P0DMS8 4/20 0.38
APLNR P35414 2/20 0.36
MAPK1 P28482 3/20 0.35
MAPT P10636 3/20 0.35
TP53 P04637 2/20 0.35
NFKB1 P19838 2/20 0.35
CYP1A2 P05177 2/20 0.35
CYP2C19 P33261 2/20 0.35
KMT2A Q03164 2/20 0.35
KDM4E B2RXH2 1/20 0.35
GMNN O75496 1/20 0.35
USP2 O75604 1/20 0.35
LMNA P02545 1/20 0.35
ESR1 P03372 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23400893 0.93 HTR2A (0.42) HTR2AHTR2CHTR2BGCGRADORA3
SCHEMBL23401292 0.89 HSD11B1 (0.40) HTR2AHTR2CHTR2BGCGRADORA3
SCHEMBL23398759 0.87 HTR2A (0.44) HTR2AHTR2CHTR2BGCGRMAPK1
SCHEMBL23398647 0.84 TP53 (0.40) GCGRADORA3MAPK1TP53NFKB1
SCHEMBL23401349 0.83 HTR2A (0.43) HTR2AHTR2CHTR2BMAPTCYP2C19
SCHEMBL23399601 0.82 HTR2A (0.40) HTR2AHTR2CHTR2BGCGRADORA3
SCHEMBL23400460 0.81 MAPT (0.40) GCGRADORA3MAPK1MAPTTP53
SCHEMBL23403169 0.81 GCGR (0.39) GCGRADORA3APLNRMAPK1MAPT
SCHEMBL23401304 0.80 HTR2A (0.41) HTR2AHTR2CHTR2BGCGRMAPK1
SCHEMBL23399315 0.80 ADORA3 (0.39) GCGRADORA3MAPK1MAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed