SCHEMBL23403191

SCHEMBL23403191

Cc1cccc(-n2nc(O)cc2CC(C)C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
CACNA1G O43497 3/20 0.40
CACNA1H O95180 3/20 0.40
KCNH2 Q12809 3/20 0.40
RIPK2 O43353 1/20 0.40
GAA P10253 1/20 0.39
MAPK1 P28482 1/20 0.39
HSD17B10 Q99714 1/20 0.39
RPA1 P27694 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HTR6 P50406 4/20 0.39
HSD11B1 P28845 1/20 0.38
LMNA P02545 2/20 0.37
MAPT P10636 2/20 0.37
TP53 P04637 1/20 0.37
SPR P35270 1/20 0.37
NPBWR1 P48145 1/20 0.36
MCHR1 Q99705 1/20 0.36
IDO1 P14902 1/20 0.36
TDO2 P48775 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23402955 0.85 KCNH2 (0.52) ALDH1A1CACNA1GCACNA1HKCNH2GAA
SCHEMBL23401563 0.84 CACNA1G (0.40) ALDH1A1CACNA1GCACNA1HKCNH2GAA
SCHEMBL23400591 0.84 ALDH1A1 (0.46) ALDH1A1RIPK2RPA1L3MBTL1HSD11B1
SCHEMBL31437775 0.83 ALDH1A1 (0.43) ALDH1A1CACNA1GCACNA1HKCNH2RIPK2
SCHEMBL23401971 0.82 ALDH1A1 (0.45) ALDH1A1RIPK2GAARPA1L3MBTL1
SCHEMBL23402256 0.80 ALDH1A1 (0.43) ALDH1A1RIPK2MAPK1RPA1L3MBTL1
SCHEMBL23403350 0.78 ALDH1A1 (0.44) ALDH1A1RIPK2GAAMAPK1HSD17B10
SCHEMBL23402339 0.78 ALDH1A1 (0.46) ALDH1A1RIPK2GAARPA1L3MBTL1
SCHEMBL23400514 0.77 ALDH1A1 (0.51) ALDH1A1RIPK2GAAMAPK1RPA1
SCHEMBL23399125 0.76 ALDH1A1 (0.42) ALDH1A1CACNA1HRIPK2GAAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed