SCHEMBL23403545

SCHEMBL23403545

CCc1c(NC(C)=O)c(=O)n(C)n1-c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 3/20 0.54
TSHR P16473 1/20 0.49
KDM4E B2RXH2 1/20 0.49
GAA P10253 5/20 0.47
KMT2A Q03164 2/20 0.46
PKM P14618 1/20 0.46
LMNA P02545 2/20 0.45
MAPT P10636 2/20 0.45
POLB P06746 2/20 0.44
GLA P06280 1/20 0.44
MEN1 O00255 1/20 0.42
F2 P00734 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23403267 0.89 FPR2 (0.53) FPR2TSHRKDM4EGAAKMT2A
SCHEMBL23401246 0.85 FPR2 (0.48) FPR2TSHRKDM4EGAAKMT2A
SCHEMBL23403509 0.85 FPR2 (0.47) FPR2TSHRKDM4EGAAKMT2A
SCHEMBL23402223 0.83 FPR2 (0.48) FPR2TSHRKDM4EGAAKMT2A
SCHEMBL23403098 0.83 FPR2 (0.46) FPR2TSHRKDM4EGAAKMT2A
SCHEMBL23403488 0.82 FPR2 (0.47) FPR2TSHRKDM4EGAAKMT2A
SCHEMBL23400077 0.81 KDM4E (0.63) FPR2TSHRKDM4EGAAKMT2A
SCHEMBL23399982 0.81 FPR2 (0.44) FPR2TSHRKDM4EGAAKMT2A
SCHEMBL23402922 0.80 KDM4E (0.51) FPR2TSHRKDM4EGAAKMT2A
SCHEMBL23401151 0.79 FPR2 (0.44) FPR2TSHRKDM4EGAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed