Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.53 |
| ▸ | TUBB | P07437 | 2/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.53 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.53 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.53 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.53 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23405224 | 0.79 | TUBB4A (0.55) | HDAC1HDAC6TUBB1TUBB4ATUBB | |
| SCHEMBL15664662 | 0.79 | TUBB4A (0.55) | HDAC1HDAC6TUBB1TUBB4ATUBB | |
| SCHEMBL14973903 | 0.76 | TUBB4A (0.51) | HDAC1HDAC6TUBB1TUBB4ATUBB | |
| SCHEMBL23405038 | 0.76 | HDAC1 (0.53) | HDAC1HDAC6TUBB1TUBB4ATUBB | |
| SCHEMBL28807093 | 0.75 | HDAC1 (0.48) | HDAC1HDAC6TUBB1TUBB4ATUBB | |
| Hydrochloric Acid SCHEMBL14974403 | 0.75 | TUBB4A (0.50) | HDAC1HDAC6TUBB1TUBB4ATUBB | |
| SCHEMBL27820762 | 0.73 | MAPT (0.47) | HDAC1HDAC6TUBB1TUBB4ATUBB | |
| SCHEMBL27915581 | 0.72 | TUBB4A (0.52) | HDAC1HDAC6TUBB1TUBB4ATUBB | |
| SCHEMBL14973767 | 0.72 | TUBB4A (0.56) | HDAC1HDAC6TUBB1TUBB4ATUBB | |
| 2-Mercaptoethanol SCHEMBL11753567 | 0.72 | HDAC1 (0.48) | HDAC1HDAC6TUBB1TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11485987-B2 | Methods for inducing bioorthogonal reactivity | UNIVERSITY OF DELAWARE (US) | 2022-11-01 | — | — | US | disclosed |
| US-20210164005-A1 | METHODS FOR INDUCING BIOORTHOGONAL REACTIVITY | UNIVERSITY OF DELAWARE (US) | 2021-06-03 | — | — | US | disclosed |
| US-20210164005-A1 | METHODS FOR INDUCING BIOORTHOGONAL REACTIVITY | UNIVERSITY OF DELAWARE (US) | 2021-06-03 | — | — | US | disclosed |