Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.44 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28807093 | 0.90 | HDAC1 (0.48) | MAPTHDAC1HDAC6ALDH1A1HPGD | |
| SCHEMBL27820756 | 0.87 | GSK3B (0.47) | HDAC1HDAC6ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL27840064 | 0.86 | MAPK14 (0.51) | MAPTALDH1A1HPGDL3MBTL1 | |
| SCHEMBL27820759 | 0.86 | HDAC1 (0.43) | MAPTHDAC1HDAC6ALDH1A1HPGD | |
| SCHEMBL27840145 | 0.84 | PDE10A (0.46) | ALDH1A1HPGDL3MBTL1TUBB4ATUBB | |
| SCHEMBL27820747 | 0.83 | CYP1A1 (0.45) | ALDH1A1HPGDL3MBTL1ABCB1DYRK1A | |
| SCHEMBL27820749 | 0.83 | GSK3B (0.48) | HDAC1HDAC6ALDH1A1HPGDMAPK1 | |
| SCHEMBL27915706 | 0.81 | MAPK14 (0.56) | MAPTHDAC1HDAC6ALDH1A1HPGD | |
| 2-Mercaptoethanol SCHEMBL11753567 | 0.81 | HDAC1 (0.48) | MAPTHDAC1HDAC6ALDH1A1HPGD | |
| SCHEMBL27934283 | 0.80 | CYP1A1 (0.45) | MAPTALDH1A1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102190625-A | Stilbene tumor targeted medicine Combretastatin A4 analogs | NANJING SANHOME PHARMACEUTICAL CO LTD | 2011-09-21 | — | — | CN | claimed |
| CN-102190625-B | Stilbene tumor targeted medicine Combretastatin A4 analogs | NANJING SANHOME PHARMACEUTICAL CO LTD | 2013-08-28 | — | — | CN | disclosed |
| CN-102190625-A | Stilbene tumor targeted medicine Combretastatin A4 analogs | NANJING SANHOME PHARMACEUTICAL CO LTD | 2011-09-21 | — | — | CN | disclosed |