SCHEMBL23405477

SCHEMBL23405477

O=P(O)(O)C=Cc1ccccc1.[LiH]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 4/20 0.46
LMNA P02545 3/20 0.46
HDAC4 P56524 3/20 0.46
ALDH1A1 P00352 2/20 0.46
HDAC3 O15379 2/20 0.46
HDAC2 Q92769 2/20 0.46
HDAC8 Q9BY41 2/20 0.46
HDAC6 Q9UBN7 2/20 0.46
PLIN1 O60240 2/20 0.46
MAPT P10636 2/20 0.46
RECQL P46063 2/20 0.46
PLIN5 Q00G26 2/20 0.46
ABHD5 Q8WTS1 2/20 0.46
TNKS O95271 1/20 0.46
HCAR2 Q8TDS4 1/20 0.46
HDAC7 Q8WUI4 1/20 0.46
HDAC10 Q969S8 1/20 0.46
HDAC11 Q96DB2 1/20 0.46
TNKS2 Q9H2K2 1/20 0.46
HDAC9 Q9UKV0 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL233260 0.98 HDAC1 (0.48) HDAC1LMNAHDAC4ALDH1A1HDAC3
SCHEMBL541471 0.98 HDAC1 (0.48) HDAC1LMNAHDAC4ALDH1A1HDAC3
SCHEMBL23405502 0.95 HDAC1 (0.46) HDAC1LMNAHDAC4ALDH1A1HDAC3
Water SCHEMBL9439968 0.95 HDAC1 (0.46) HDAC1LMNAHDAC4ALDH1A1HDAC3
SCHEMBL27406196 0.95 HDAC1 (0.47) HDAC1LMNAHDAC4ALDH1A1HDAC3
SCHEMBL23405490 0.95 HDAC1 (0.46) HDAC1LMNAHDAC4ALDH1A1HDAC3
SCHEMBL8712443 0.90 TSHR (0.48) HDAC1LMNAHDAC4ALDH1A1HDAC3
Styrene SCHEMBL7612533 0.88 ALDH1A1 (0.54) HDAC1LMNAHDAC4ALDH1A1HDAC3
SCHEMBL9815253 0.84 HDAC1 (0.48) HDAC1LMNAHDAC4ALDH1A1HDAC3
SCHEMBL9815254 0.84 HDAC1 (0.48) HDAC1LMNAHDAC4ALDH1A1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3845606-B1 HYDROGEL AND USES THEREFOR SEKISUI KASEI CO LTD (JP) 2026-02-18 EP disclosed
US-12415895-B2 Hydrogel and uses therefor SEKISUI KASEI CO., LTD. (JP) 2025-09-16 US disclosed
EP-3845606-A1 HYDROGEL AND USES THEREFOR Sekisui Kasei Co., Ltd. (JP) 2021-07-07 EP disclosed
US-20210163694-A1 HYDROGEL AND USES THEREFOR SEKISUI KASEI CO., LTD. (JP) 2021-06-03 US disclosed
CN-112533997-A Hydrogels and uses thereof 积水化成品工业株式会社 2021-03-19 CN disclosed