SCHEMBL541471

SCHEMBL541471

O=P(O)(O)/C=C/c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 4/20 0.48
LMNA P02545 3/20 0.48
HDAC4 P56524 3/20 0.48
ALDH1A1 P00352 2/20 0.48
HDAC3 O15379 2/20 0.48
HDAC2 Q92769 2/20 0.48
HDAC8 Q9BY41 2/20 0.48
HDAC6 Q9UBN7 2/20 0.48
PLIN1 O60240 2/20 0.48
MAPT P10636 2/20 0.48
RECQL P46063 2/20 0.48
PLIN5 Q00G26 2/20 0.48
ABHD5 Q8WTS1 2/20 0.48
TNKS O95271 1/20 0.48
HCAR2 Q8TDS4 1/20 0.48
HDAC7 Q8WUI4 1/20 0.48
HDAC10 Q969S8 1/20 0.48
HDAC11 Q96DB2 1/20 0.48
TNKS2 Q9H2K2 1/20 0.48
HDAC9 Q9UKV0 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL233260 1.00 HDAC1 (0.48) HDAC1LMNAHDAC4ALDH1A1HDAC3
SCHEMBL23405502 0.98 HDAC1 (0.46) HDAC1LMNAHDAC4ALDH1A1HDAC3
Water SCHEMBL9439968 0.98 HDAC1 (0.46) HDAC1LMNAHDAC4ALDH1A1HDAC3
SCHEMBL23405490 0.98 HDAC1 (0.46) HDAC1LMNAHDAC4ALDH1A1HDAC3
SCHEMBL27406196 0.98 HDAC1 (0.47) HDAC1LMNAHDAC4ALDH1A1HDAC3
SCHEMBL23405477 0.98 HDAC1 (0.46) HDAC1LMNAHDAC4ALDH1A1HDAC3
SCHEMBL8712443 0.92 TSHR (0.48) HDAC1LMNAHDAC4ALDH1A1HDAC3
Styrene SCHEMBL7612533 0.90 ALDH1A1 (0.54) HDAC1LMNAHDAC4ALDH1A1HDAC3
SCHEMBL9815253 0.86 HDAC1 (0.48) HDAC1LMNAHDAC4ALDH1A1HDAC3
SCHEMBL9815254 0.86 HDAC1 (0.48) HDAC1LMNAHDAC4ALDH1A1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119897215-A Beneficiation method for enhanced recovery of tungsten and fluorite in sulfide ore flotation tailings 长沙矿冶研究院有限责任公司 2025-04-29 CN claimed
CN-119372801-A Antibacterial regenerated PET elastic fiber and preparation method thereof 江苏卡乐纺新材料有限公司 2025-01-28 CN claimed
US-20170362255-A1 LIGAND-EXCHANGEABLE NANOPARTICLES AND METHODS OF MAKING THE SAME Alliance for Energy Innovation, LLC 2017-12-21 US claimed
US-20060051648-A1 Solid polymer electrolyte membrane, method for producing the same, and fuel cell including the solid poymer electrolyte membrane SAMSUNG SDI CO. LTD. (KR) 2006-03-09 US claimed
US-5912274-A WATER INSOLUBLE NONCATIONIC ANTIBACTERIAL PHENOL CONTAINING, RELATIVE TO THE HYDROXYL GROUP, AN ALKYL OR CYCLOALKYL GROUP, PREFERABLY TERT.-BUTYL (T-BUTYL), IN THE 2-POSITION, AND SUBSTITUENTS IN ONE OR BOTH OF THE 4- AND 5-POSITIONS COLGATE-PALMOLIVE COMPANY (US) 1999-06-15 US claimed
EP-0852486-A2 ANTIPLAQUE ORAL COMPOSITION Colgate-Palmolive Company (US) 1998-07-15 EP claimed
US-5723500-A WATER INSOLUBLE, NONCATIONIC, ANTIBACTERIAL, STERICALLY HINDERED PHENOL; MOUTHWASHES, DENTIFRICES COLGATE-PALMOLIVE COMPANY (US) 1998-03-03 US claimed
US-5686064-A MIXTURE INCLUDES TETRAALKALI METAL POLYPHOSPHATE AND TRICLOSAN; DENTIFRICES COLGATE PALMOLIVE COMPANY (US) 1997-11-11 US claimed
WO-1997010800-A2 ANTIPLAQUE ORAL COMPOSITION COLGATE-PALMOLIVE COMPANY (US) 1997-03-27 WO claimed
US-5294431-A Aqueous vehicle, noncationic bactericide, surfactant, flavoring oil, alcohol and a bactericide promoter enhancing delivery and adhesion; phosphate-free COLGATE-PALMOLIVE CO. (US) 1994-03-15 US claimed
US-5288480-A Antiplaque antibacterial oral composition COLGATE-PALMOLIVE CO. (US) 1994-02-22 US claimed
US-5032386-A Dentistry COLGATE-PALMOLIVE COMPANY (US) 1991-07-16 US claimed
EP-0036174-B1 PROCESS FOR PREPARING 2-PHENYLETHYLENE PHOSPHONIC ACID Henkel Kommanditgesellschaft auf Aktien (DE) 1983-02-16 EP claimed
EP-0036174-A2 Process for preparing 2-phenylethylene phosphonic acid Henkel Kommanditgesellschaft auf Aktien (DE) 1981-09-23 EP claimed
JP-2288819-A None JP disclosed
US-12365830-B2 Ligand-exchangeable janus nanoparticles and methods of making the same ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2025-07-22 US disclosed
CN-119372801-A Antibacterial regenerated PET elastic fiber and preparation method thereof 江苏卡乐纺新材料有限公司 2025-01-28 CN disclosed
EP-0036174-A2 Process for preparing 2-phenylethylene phosphonic acid Henkel Kommanditgesellschaft auf Aktien (DE) 1981-09-23 EP disclosed
EP-0023314-A1 Process for preparing poly(arylene sulfides) BAYER AG (DE) 1981-02-04 EP disclosed
US-4113841-A METAL SALT OF ORGANIC PHOSPHONIC ACID HOECHST AKTIENGESELLSCHAFT (DE) 1978-09-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170362255-A1 LIGAND-EXCHANGEABLE NANOPARTICLES AND METHODS OF MAKING THE SAME CA6, CA13, EPCAM HDAC1 2208/4885LMNA 1880/4885HDAC4 2195/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.