Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 3/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15103569 | 0.93 | HTR4 (0.51) | HTR4 | |
| SCHEMBL15103514 | 0.92 | HTR4 (0.51) | HTR4OPRL1OPRM1 | |
| SCHEMBL15103570 | 0.92 | HTR4 (0.49) | HTR4OPRL1OPRM1 | |
| SCHEMBL15103640 | 0.91 | HTR4 (0.49) | HTR4OPRL1OPRM1 | |
| SCHEMBL2337050 | 0.88 | HTR4 (0.55) | HTR4CNR2 | |
| SCHEMBL2334242 | 0.88 | HTR4 (0.52) | HTR4CNR2OPRL1OPRM1 | |
| Hydrochloric Acid SCHEMBL3295752 | 0.87 | HTR4 (0.51) | HTR4CNR2OPRL1OPRM1 | |
| SCHEMBL3301384 | 0.85 | HTR4 (0.49) | HTR4CNR2OPRL1OPRM1 | |
| SCHEMBL3369956 | 0.81 | HTR4 (0.58) | HTR4 | |
| SCHEMBL2333382 | 0.81 | HTR4 (0.56) | HTR4CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358702-B1 | PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE | SK BIOPHARMACEUTICALS CO LTD (KR) | 2013-07-17 | — | — | EP | disclosed |
| EP-2358702-A2 | PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE | SK Holdings Co., Ltd. (KR) | 2011-08-24 | — | — | EP | disclosed |
| WO-2010044585-A2 | PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE | SK HOLDINGS CO., LTD. (KR) | 2010-04-22 | — | — | WO | disclosed |