Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.37 |
| ▸ | MAP3K7 | O43318 | 4/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.34 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2235586 | 0.86 | IRAK4 (0.46) | PIM1DYRK3CCNT1CDK9DYRK1A | |
| SCHEMBL14881665 | 0.84 | PIM1 (0.42) | PIM1DYRK3CCNT1CDK9DYRK1A | |
| SCHEMBL14882280 | 0.84 | PIM1 (0.42) | PIM1DYRK3CCNT1CDK9DYRK1A | |
| SCHEMBL21765939 | 0.84 | PDE10A (0.44) | PIM1DYRK3CCNT1CDK9DYRK1A | |
| SCHEMBL15273512 | 0.81 | PTPN11 (0.41) | PIM1DYRK3CCNT1CDK9DYRK1A | |
| SCHEMBL15258062 | 0.81 | HRH4 (0.46) | NTRK1NTRK3NTRK2 | |
| SCHEMBL26129364 | 0.81 | AAK1 (0.41) | PIM1DYRK3CCNT1CDK9DYRK1A | |
| SCHEMBL23408576 | 0.81 | PIM1 (0.40) | PIM1DYRK3CCNT1CDK9DYRK1A | |
| SCHEMBL15273513 | 0.81 | HRH4 (0.46) | NTRK1NTRK3NTRK2 | |
| SCHEMBL24074245 | 0.80 | HTT (0.51) | PIM1DYRK3CCNT1CDK9DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021098745-A1 | PREPARATION AND APPLICATION OF A CLASS OF PROTEIN RECEPTOR KINASE INHIBITORS | 上海轶诺药业有限公司 | 2021-05-27 | — | — | WO | disclosed |