Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 5/20 | 0.47 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15103569 | 0.80 | HTR4 (0.51) | HTR4 | |
| SCHEMBL2340840 | 0.76 | HTR4 (0.49) | HTR4 | |
| SCHEMBL15103514 | 0.76 | HTR4 (0.51) | HTR4 | |
| SCHEMBL15103570 | 0.76 | HTR4 (0.49) | HTR4 | |
| SCHEMBL2334884 | 0.76 | HTR4 (0.46) | HTR4TPSAB1 | |
| SCHEMBL2338629 | 0.76 | HTR4 (0.44) | HTR4 | |
| SCHEMBL15103640 | 0.75 | HTR4 (0.49) | HTR4HTR2A | |
| SCHEMBL2333567 | 0.74 | HTR4 (0.45) | HTR4FAAHACHE | |
| SCHEMBL2337617 | 0.74 | HTR4 (0.41) | HTR4F10ASAH1CACNA1GCACNA1H | |
| SCHEMBL2335601 | 0.73 | HTR4 (0.55) | HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358702-A2 | PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE | SK Holdings Co., Ltd. (KR) | 2011-08-24 | — | — | EP | disclosed |
| WO-2010044585-A2 | PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE | SK HOLDINGS CO., LTD. (KR) | 2010-04-22 | — | — | WO | disclosed |