Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985736 | 0.82 | MAPT (0.56) | MAPTKDM4ERAB9AHTTALDH1A1 | |
| SCHEMBL9375468 | 0.82 | MAPT (0.61) | MAPTKDM4ERAB9AHTTALDH1A1 | |
| SCHEMBL6368454 | 0.82 | MAPT (0.56) | MAPTKDM4ERAB9AHTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL9373275 | 0.80 | MAPT (0.59) | MAPTKDM4ERAB9AHTTALDH1A1 | |
| SCHEMBL2557513 | 0.79 | MAPT (0.53) | MAPTKDM4ERAB9AHTTALDH1A1 | |
| Bromide SCHEMBL7518700 | 0.79 | MAPT (0.53) | MAPTKDM4ERAB9AHTTALDH1A1 | |
| Bromide SCHEMBL7518696 | 0.79 | MAPT (0.53) | MAPTKDM4ERAB9AHTTALDH1A1 | |
| SCHEMBL3822633 | 0.78 | ALDH1A1 (0.66) | MAPTKDM4ERAB9AHTTALDH1A1 | |
| SCHEMBL15511813 | 0.77 | MAPT (0.56) | MAPTKDM4ERAB9AHTTALDH1A1 | |
| SCHEMBL7518703 | 0.77 | MAPT (0.51) | MAPTKDM4ERAB9AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358343-A2 | METHOD FOR DECOLOURING KERATINOUS FIBRES | Henkel AG & Co. KGaA (DE) | 2011-08-24 | — | — | EP | claimed |
| WO-2010072512-A2 | METHOD FOR DECOLOURING KERATINOUS FIBRES | HENKEL AG & CO. KGAA (DE) | 2010-07-01 | — | — | WO | claimed |
| US-20130065875-A1 | SMALL MOLECULE INHIBITORS OF HEPATITIS C VIRUS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2013-03-14 | — | — | US | disclosed |
| US-8362020-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-01-29 | — | — | US | disclosed |
| US-20110046157-A1 | Substituted hydroxamic acids and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-02-24 | — | — | US | disclosed |
| CN-101213174-A | Oxindole compounds and their uses as therapeutic agents | XENON PHARMACEUTICALS INC (CA) | 2008-07-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065875-A1 | SMALL MOLECULE INHIBITORS OF HEPATITIS C VIRUS | HAVCR2, FABP1, LIPC | MAPT 3352/4885KDM4E 2553/4885RAB9A 1369/4885 |
| US-20110046157-A1 | Substituted hydroxamic acids and uses thereof | HDAC6, HDAC5, HDAC1 | MAPT 2380/4885KDM4E 903/4885RAB9A 2388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.