Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.66 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.62 |
| ▸ | TP53 | P04637 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | RAF1 | P04049 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12388808 | 0.91 | APOBEC3A (0.71) | APOBEC3AAPOBEC3GNPSR1TP53RAB9A | |
| SCHEMBL14363236 | 0.87 | KCNMA1 (0.77) | TP53RAB9AMAPTKMT2ATDP1 | |
| SCHEMBL5310996 | 0.85 | KCNMA1 (0.73) | APOBEC3AAPOBEC3GNPSR1TP53RAB9A | |
| SCHEMBL5789916 | 0.84 | MAPT (0.57) | APOBEC3AAPOBEC3GNPSR1TP53RAB9A | |
| SCHEMBL7304022 | 0.84 | HTT (0.67) | APOBEC3AAPOBEC3GNPSR1TP53RAB9A | |
| SCHEMBL2559603 | 0.83 | APOBEC3A (0.61) | APOBEC3AAPOBEC3GNPSR1TP53RAB9A | |
| SCHEMBL25068906 | 0.83 | DEGS1 (0.52) | NPSR1TP53RAB9AMAPTKMT2A | |
| SCHEMBL15730781 | 0.82 | MAPK14 (0.74) | TP53RAB9AMAPTKMT2ATDP1 | |
| SCHEMBL12190897 | 0.81 | CHRNA7 (0.55) | APOBEC3AAPOBEC3GNPSR1TP53RAB9A | |
| SCHEMBL6029542 | 0.81 | KCNMA1 (0.84) | TP53RAB9AMAPTKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021099842-A1 | PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO INC. (CA) | 2021-05-27 | — | — | WO | disclosed |