Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTBK1 | Q5TCY1 | 8/20 | 0.59 |
| ▸ | TTBK2 | Q6IQ55 | 8/20 | 0.59 |
| ▸ | BTK | Q06187 | 4/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HPGDS | O60760 | 1/20 | 0.48 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29729076 | 0.98 | TTBK1 (0.58) | TTBK1TTBK2BTKHDAC6HPGDS | |
| SCHEMBL16266363 | 0.85 | TTBK1 (0.61) | TTBK1TTBK2BTKHDAC6TNNI3K | |
| SCHEMBL22909512 | 0.84 | TTBK1 (0.57) | TTBK1TTBK2BTKHDAC6HPGDS | |
| SCHEMBL29665587 | 0.83 | TTBK1 (0.62) | TTBK1TTBK2BTKHDAC6HPGDS | |
| SCHEMBL30485458 | 0.83 | TTBK1 (0.62) | TTBK1TTBK2BTKHDAC6HPGDS | |
| SCHEMBL23409027 | 0.83 | TTBK1 (0.62) | TTBK1TTBK2BTKHDAC6HPGDS | |
| SCHEMBL28451436 | 0.83 | TTBK1 (0.62) | TTBK1TTBK2BTKHDAC6HPGDS | |
| SCHEMBL25069022 | 0.83 | TTBK1 (0.56) | TTBK1TTBK2BTKHDAC6HPGDS | |
| Hydrochloric Acid SCHEMBL29729054 | 0.82 | TTBK1 (0.61) | TTBK1TTBK2BTKHDAC6HPGDS | |
| SCHEMBL23409023 | 0.81 | GAA (0.57) | TTBK1TTBK2BTKHDAC6HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230055961-A1 | PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | DUNAD THERAPEUTICS LTD. (GB) | 2023-02-23 | — | — | US | disclosed |
| WO-2021099842-A1 | PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO INC. (CA) | 2021-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230055961-A1 | PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | FURIN, PFAS, CFTR | TTBK1 3603/4885TTBK2 2919/4885BTK 305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.